Technologies 

Complement C3d-binding peptide carriers. 

Potent and Highly Soluble PEGylated Compstatin Peptides. UCR-Link  

C3d-binding Biomarkers for Detection of Complement-mediated Inflammation. UCR-Link  

Functionally Selective Ligands for Study and Inhibition of Inflammation. UCR-Link   

Novel Compstatin Analogs for the Treatment of Inflammatory and Autoimmune Diseases. UCR-Link 

Patents

Complement C3d-binding peptide carriers. US Provisional Patent Application 62/784,196, UC Case No. 2019-115-1. Inventors: Morikis D, Mohan RR, Harrison RES. 

Potent and highly soluble PEGylated compstatin peptides. US Patent Application 15/685,364, UC Case No. 2017-046-2. Inventors: Morikis D, Mohan RR, Harrison RES, Gorham RD Jr, Cabrera AP, Ghosh K.

Discovery of the first selective C5a2 receptor (C5L2/C5aR2) ligands. US Patent Application 15/295,979, UC Case No. 2016-024-2. Inventors: Morikis D, Floudas CA, Woodruff TM, Monk PN, Cooper MA, Croker DE.

Complement C3d-binding compounds. US Patent Application 15/567,953, UC Case No. 2014-619-2. Inventors: Morikis D, Gorham RD Jr.

Compstatin analogs. US Patent 9,512,180, UC Case No. 2012-461-3. Inventors: Morikis D, Gorham RD Jr, Khoury GA, Bellows-Peterson ML, Floudas CA, Tamamis P, Archontis G.

Molecular dynamics in drug design: new generations of compstatin analogs. US Provisional Patent Application Nos 61/585146 and 61/739438 (2012, 2013), Inventors: Morikis D, López de Victoria A, Gorham RD Jr, Bellows-Peterson ML, Tamamis P, Floudas CA, Archontis G.

Novel C3aR agonists and antagonists. US Provisional Patent Application No 61/635008  (2012, 2013). Inventors: Bellows-Peterson ML, Floudas CA, Morikis D, Monk PN, Woodruff TM.

C3aR antagonists. US Provisional Patent Application No 61/273071 (2009). Inventors: Floudas CA, Fung HK, Bellows ML, Kieslich CA, Zhang L, Morikis D.

Compstatin Variants. US Provisional Patent Applications No. 61/137399 (2008, 2009, 2010, 2011). Inventors: Floudas CA, Bellows ML, Morikis D.

Compstatin analogs identified by computer modeling and optimization. US Provisional Patent Application No. 60/412277 (2002). Inventors: Lambris JD, Floudas CA, Morikis D.

New peptides and peptidomimetics based on compstatin; Peptides and peptidomimetics for inhibiting complement activation. WO9913899­A, WO9913899­A1, AU9746481­A, PCT/US97/16850 (1997, 1999). Inventors: Lambris JD, Morikis D.

Copyrighted Software

ComPy_AP. Software for quantitative modeling of the alternative pathway of the complement system. 2016. Authors: Zewde N, Gorham RD Jr, Morikis D.